Technologieangebote Life Sciences

Die Biotechnologie- und die Life Sciences-Branche in Berlin und Brandenburg hat in den vergangenen Jahren ein rasantes Wachstum durchlaufen, dessen Ende sich noch nicht abzeichnet. Zahlreiche Ausgründungen aus Berlins Universitäten und Forschungseinrichtungen haben dazu beigetragen, Berlin und die Hauptstadtregion zu einem ernstzunehmenden europäischen Wirtschafts- und Forschungsstandort für die Life Sciences Industrie werden zu lassen.

Die Life Sciences Projektmanager der ipal GmbH verfügen auf dieser Plattform über hervorragende Kontakte. Sollten Sie Fragen zu den hier aufgeführten oder Ihren eigenen Patentlösungen haben, dann nehmen Sie bitte mit uns Kontakt auf.

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  Kategorie:

  Research Tools

  09038 18-10-2009

  Enabling Technology: Assessment of Antigen- Specific T Cell Functions

  We offer a highly sensitive, non-radioactive method for the functional detection of antigen-specific T-lymphocytes ex vivo. The technology is based on module based vectors constructed in a way that an antigen and a fluorescence marker directly correlate in their expression. Furthermore, subsequent separation of the marker from the antigen protects it from degradation and results in a strong fluorescence signal. The method is based on the Plasmid Transfection Fluorolysis (PTF) Assay developed by the inventors as well.

  Projektstatus:

  Proof of Principle

  Projektmanager:

  Dr. Janin Hofmann

   Exposé zum Download
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  Kategorie:

  Medizintechnik & Rehabilitationstechnik

  07147 14-09-2009

  A Bone Cement Composition for the Creation of a MRT-Signaling Bone Cement

  

  Bone cements based on polymethylmethacrylate (PMMA) are mostly used for the anchorage of artificial joints, as bone substitutes at backbone diseases or after tumor surgeries, for the encouragement of implants (e.g. plates, nails) or as placeholder in infected joints. Most bone cements are produced by the combination of a 2-phase-system, containing a powder (PMMA) and a fluid (MMA). Especially in the new field of the so called “open MRT” (insertion of bone cement into fractured vertebral bodies or cleared tumor caves) it is necessary to follow the operation process by MR imaging to ensure the right position of the bone cement. Therefore the researchers developed bone cement with paramagnetic properties to induce a MRT detectable signal (see figure above, arrow). They added sodium chloride solution containing a contrast agent to the MMA and proceeded as done by common bone cement production. In this way they achieved modified bone cement that can induce a MR signal by keeping all conventional properties.

  Projektstatus:

  Proof of Concept

  Projektmanager:

  Dr. Janin Hofmann

   Exposé zum Download
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  Kategorie:

  Chemie & Bioverfahrenstechnik (weiße Biotechnologie)

  08065 21-08-2009

  Evolutionary Process for Catalyst Development

  The inventive process combines evolutionary strategies (ES) including crossover, selection and mutation with genetic algorithms (GA) as an optimization method for the development of heterogeneous catalytic materials. The GA serves to find the optimal combination of catalyst components and the preparation method, whereas the ES is used to find the optimal quantity of each component. The method is preferably used for catalysts consisting of 3 or more single components, whereby the first catalyst generation is randomly generated. The optimal composition for the requested catalyst with high activity, selectivity and yield is mostly achieved after 5 to 10 generations.

  Projektstatus:

  Product

  Projektmanager:

  Dr. Andreas Voigt

   Exposé zum Download
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  Kategorie:

  Neurologie

  08185 21-08-2009

  Opioid Receptor Antagonists for Acute Treatment of Paraphilic Arousal States

  The present invention provides a method for acute treatment of paraphilic sexual arousal states in patients suffering from paraphilia by administering an opioid receptor antagonist.

  Projektstatus:

  Product

  Projektmanager:

  Dr. Janin Hofmann

   Exposé zum Download
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  Kategorie:

  Medizintechnik & Rehabilitationstechnik

  07152 21-07-2009

  Thixotropic Doxorubicin-Gel (TDG)

  

  The scientists developed a polymer-free, lipid-free hydrogel of a doxorubicin compound and a method of producing such hydrogel. The hydrogel has thixotropic properties, making it useful for the coating of medical devises. So the hydrogel can be used to coat balloon catheters and thereby helps to prevent restenosis after angioplasty.

  Projektstatus:

  Lab Level

  Projektmanager:

  Dr. Andreas Voigt

   Exposé zum Download