Technologieangebote Life Sciences

Die Biotechnologie- und die Life Sciences-Branche in Berlin und Brandenburg hat in den vergangenen Jahren ein rasantes Wachstum durchlaufen, dessen Ende sich noch nicht abzeichnet. Zahlreiche Ausgründungen aus Berlins Universitäten und Forschungseinrichtungen haben dazu beigetragen, Berlin und die Hauptstadtregion zu einem ernstzunehmenden europäischen Wirtschafts- und Forschungsstandort für die Life Sciences Industrie werden zu lassen.

Die Life Sciences Projektmanager der ipal GmbH verfügen auf dieser Plattform über hervorragende Kontakte. Sollten Sie Fragen zu den hier aufgeführten oder Ihren eigenen Patentlösungen haben, dann nehmen Sie bitte mit uns Kontakt auf.

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  Kategorie:

  Zentrales Nervensystem

  08135 29-10-2009

  A Stable Cell Line that is Inducible to Express hsTRPM2

  Use of the Flip-In T-Rex-HEK293 cell line enables the integration of the gen into a specific tanscription-active position of the genome and allows to control gen expression by tetracyclin.

  Projektstatus:

  Product

  Projektmanager:

  Rafaela Kunz

   Exposé zum Download
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  Kategorie:

  Infektionskrankheiten

  07060 22-10-2009

  Immortalized Human Cell Line For HIV Phenotyping

  The invention provides an immortalized human CD4-positive T cell line from a donor homozygous negative for the chemokine receptor CCR5 to determine the coreceptor usage of HIV-1 isolates. The cells are resistant to infection with CCR5-tropic HIV viruses, but are highly susceptible to infection with CXCR4-tropic isolates. This cell line is therefore suitable for a wide range of application: in basic research, e.g. for signal transduction studies, pharmacological studies and clinical application of CCR5 antagonists.

  Projektstatus:

  Prototype

  Projektmanager:

  Rafaela Kunz

   Exposé zum Download
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  Kategorie:

  Autoimmunkrankheiten & Entzündungen

  07089 22-10-2009

  Functionalized Nanoparticles as Novel Anti-Inflammatory Drugs

  Leukocyte-endothelial cell interaction plays an important role in acute and chronic inflammatory processes. The involvement of the cell adhesion molecules E-, P- and L-selectin and their ligands makes them to suitable targets for diagnosis and therapy.High-affinity inhibitors of selectin-ligand interaction are offered, suitable for the treatment of a wide range of inflammatory diseases, such as Rheumatoid Arthritis and other autoimmune disorders. The novel functionalized gold nanoparticles exhibit excellent selectin-inhibitory capacity with IC50 in the lower picomolar range and a far higher affinity for selectins than any other known selectin-inhibitor.

  Projektstatus:

  in vitro

  Projektmanager:

  Rafaela Kunz

   Exposé zum Download
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  Kategorie:

  Diagnostika & diagnostische Verfahren

  09042 19-10-2009

  Novel Marker for Diagnosis of Celiac Disease

  Here we provide a novel marker, which exhibits a higher sensitivity than any other known diagnostic test for celiac disease. Furthermore, the novel marker features the detection by antibodies from patient sera under denaturated conditions, which allows the design of various assay formats of diagnostic kits.

  Projektstatus:

  Diagnostic Assay

  Projektmanager:

  Dr. Andreas Voigt

   Exposé zum Download
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  Kategorie:

  Pharma & rote Biotechnologie

  09061 19-10-2009

  Bisphosphonates as Inhibitors for Acid Sphingomyelinase

  The invention therefore offers simple geminal bisphosphonates with a prolonged carbon chain as potent and selective inhibitors of the acid sphingomyelinase. The compounds can be synthesized in a one-step procedure and show clear inhibition of cell death in vitro. License

  Projektstatus:

  ex vivo

  Projektmanager:

  Dr. Andreas Voigt

   Exposé zum Download