Technologieangebote Life Sciences
Die Biotechnologie- und die Life Sciences-Branche in Berlin und Brandenburg hat in den vergangenen Jahren ein rasantes Wachstum durchlaufen, dessen Ende sich noch nicht abzeichnet. Zahlreiche Ausgründungen aus Berlins Universitäten und Forschungseinrichtungen haben dazu beigetragen, Berlin und die Hauptstadtregion zu einem ernstzunehmenden europäischen Wirtschafts- und Forschungsstandort für die Life Sciences Industrie werden zu lassen.
Die Life Sciences Projektmanager der ipal GmbH verfügen auf dieser Plattform über hervorragende Kontakte. Sollten Sie Fragen zu den hier aufgeführten oder Ihren eigenen Patentlösungen haben, dann nehmen Sie bitte mit uns Kontakt auf.
Ergebnisse 1 bis 5 von insgesamt 49
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- Kategorie:
- Diagnostics
Aptamers for Treatment and Diagnosis of Autoantibody Based Dilated Cardiomyopathy
- We offer novel high affinity aptamers which inhibit the agonistic effect of autoantibodies specific for the second extracellular loop of human beta1-adrenergic receptors. Antibodies to the beta1- adrenergic receptor are detected in approximately 70% of idiopathic dilated cardiomyopathy patients and in nearly 100% of patients with Chagas’ cardiomyopathy and peripartum cardiomyopathy.
- Projektstatus:
- In vitro
- Projektmanager:
- Dr. Bettina Büttner
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- Kategorie:
- Research Tools
Method for Identification of Proteasome Generated Spliced Peptides (e. g. Antigenic Peptides)
- A method for the identification of proteasomal spliced peptides (PSP) of a parental protein comprising a new software called “SpliceMet”, an in vitro substrate digestion assay and mass spectrometrical (MS) analysis. The method has the great potential to identify yet unknown MHC-I- presented epitopes e.g. tumor-derived or infectious agent–derived antigens. Such new identified PSP-antigens could be used to develop antigen-based combination vaccines for the treatment and/or prophylaxis of tumor and infection diseases.
- Projektstatus:
- Proof of Concept
- Projektmanager:
- Dr. Bettina Büttner
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- Kategorie:
- Pharma & rote Biotechnologie
Pharmaceutical Composition for the Treatment of Solar Urticaria
- A lidocaine/prilocaine combination for topical application prior to UV-provocation for the treatment or prevention of solar urticaria. It stabilizes or inhibits sensory nerve fibres of the skin and induces down-regulation or inhibition of the release of pro-inflammatory neuropeptides.
- Projektstatus:
- Clinical
- Projektmanager:
- Dr. Janin Hofmann
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- Kategorie:
- Ernährung & Grüne Biotechnologie
Novel compounds for cytokinin oxidase inhibition in plants
- Internal cytokinin levels influence growth and morphology in higher plants. The amount of cytokinin present in a plant or plant tissue is strongly controlled by a signalling pathway involving cytokinin oxidase (CKX) as one major component. Antisense inhibition of CKX activity leads to a stimulation of root growth, retardation of senescence and the production of a higher number of inflorescences. The novel class of purin derivatives inhibiting CKX activity leads to a similar effect on higher plants as the antisense technique. Treatments of human cell cultures with the novel purin derivatives reveal also a beneficial effect in respect to ageing.
- Projektstatus:
- Experiments in model plan Arabidopsis, tabacco and first results in rape
- Projektmanager:
- Dr. Bettina Büttner
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- Kategorie:
- Ernährung & Grüne Biotechnologie
Novel Cytokinin Receptor Antagonists
- 2,6-Disubstituted Purine Derivatives as Cytokinin Receptor Antagonists for Influencing Plant Morphology. These novel purine derivatives act as plant growth regulators; they stimulate root growth (branching), accelerate seed germination and increase the fruit and grain size, shorten germination period and regulate proliferation and morphogenesis in tissue culture.
- Projektstatus:
- Experiment in model plant Arabidopsis
- Projektmanager:
- Dr. Bettina Büttner
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