Technologieangebote Life Sciences
Die Biotechnologie- und die Life Sciences-Branche in Berlin und Brandenburg hat in den vergangenen Jahren ein rasantes Wachstum durchlaufen, dessen Ende sich noch nicht abzeichnet. Zahlreiche Ausgründungen aus Berlins Universitäten und Forschungseinrichtungen haben dazu beigetragen, Berlin und die Hauptstadtregion zu einem ernstzunehmenden europäischen Wirtschafts- und Forschungsstandort für die Life Sciences Industrie werden zu lassen.
Die Life Sciences Projektmanager der ipal GmbH verfügen auf dieser Plattform über hervorragende Kontakte. Sollten Sie Fragen zu den hier aufgeführten oder Ihren eigenen Patentlösungen haben, dann nehmen Sie bitte mit uns Kontakt auf.
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- Kategorie:
- Ernährung & Grüne Biotechnologie
Novel compounds for cytokinin oxidase inhibition in plants
- Internal cytokinin levels influence growth and morphology in higher plants. The amount of cytokinin present in a plant or plant tissue is strongly controlled by a signalling pathway involving cytokinin oxidase (CKX) as one major component. Antisense inhibition of CKX activity leads to a stimulation of root growth, retardation of senescence and the production of a higher number of inflorescences. The novel class of purin derivatives inhibiting CKX activity leads to a similar effect on higher plants as the antisense technique. Treatments of human cell cultures with the novel purin derivatives reveal also a beneficial effect in respect to ageing.
- Projektstatus:
- Experiments in model plan Arabidopsis, tabacco and first results in rape
- Projektmanager:
- Dr. Bettina Büttner
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- Kategorie:
- Ernährung & Grüne Biotechnologie
Means and Method for the Production of transgenic plants that are resistant to clubroot
- A new transgenic approach for achieving clubroot resistance in Brassicacea. By tissue-specific expression of an enzyme able to decrease cytokinin status, in hypocotyl and root, plants can be generated with resistance to the pathogen Plasmordiophora brassicae without affecting the cytokinin content in other tissues.
- Projektstatus:
- Proof of principle in model plant Arabidopsis
- Projektmanager:
- Dr. Bettina Büttner
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- Kategorie:
- Ernährung & Grüne Biotechnologie
Novel Cytokinin Receptor Antagonists
- 2,6-Disubstituted Purine Derivatives as Cytokinin Receptor Antagonists for Influencing Plant Morphology. These novel purine derivatives act as plant growth regulators; they stimulate root growth (branching), accelerate seed germination and increase the fruit and grain size, shorten germination period and regulate proliferation and morphogenesis in tissue culture.
- Projektstatus:
- Experiment in model plant Arabidopsis
- Projektmanager:
- Dr. Bettina Büttner
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- Kategorie:
- Ernährung & Grüne Biotechnologie
rock2 and rock3, two new gain-of-function variants of the cytokinin receptors AHK2 and AHK3
- Novel constitutive active variants of the cytokinin receptors AHK2 and AHK3, originally found in a specific Arabidopsis mutant, can be used to generate transgenic plants (economic plants) with improved productivity and growth characteristics (enhanced vegetative growth).
- Projektstatus:
- Model plant Arabidopsis
- Projektmanager:
- Dr. Bettina Büttner
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- Kategorie:
- Impfstoffe
Vaccination Strategy for the Treatment of Alzheimer's Disease
- The invention provides a new vaccination strategy for the treatment or prevention of neurodegenerative diseases like Alzheimer’s disease, which is known to be the major cause of dementia. The inventors developed retrovirus-like particles who present the human amyloidal b42-peptide on their surface. The presented epitop causes a strong B- but no T-cell response and can therefore be used as immunization agent.
- Projektstatus:
- in vivo (mouse model)
- Projektmanager:
- Rafaela Kunz
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